This not only gets the performance gains of defragmentation, but also enforces more contiguous/sequential write I/Os which is beneficial for the SAN environment. IntelliWrite is especially advantageous for storage technologies such as Virtual and SAN storage systems. ![]() IntelliWrite® fragmentation prevention technology IntelliWrite proactively prevents up to 85% of file fragmentation from ever occurring, dramatically improving application and storage performance on Windows® machines with no resource usage. The following features bring about systems that are much faster, energy friendly and require less maintenance. With the release of Diskeeper 12, only the following editions will be available: Diskeeper allows you to focus on your business not IT by keeping your systems running like new improving business productivity and extending the time between technology refreshes. Diskeeper’s proactive enterprise level technology prevents file fragmentation before it starts. It runs transparently and proactively 24/7 to accelerate file I/O ensuring peak application and storage performance.ĭiskeeper® 12 brings a critical efficiency boost that is constant, automatic and cost-effective. That is where Diskeeper® 12 performance software comes in. Slow performance can bottleneck a whole system slowing your applications. Latest Product Information Diskeeper 12 FeaturesĬPU and memory performance has increased geometrically while storage performance has lagged behind.
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![]() Headquartered in Greater Montréal, Québec, Bombardier operates aerostructure, assembly and completion facilities in Canada, the United States and Mexico. Bombardier aircraft are also trusted around the world in government and military special-mission roles leveraging Bombardier Defense’s proven expertise. Bombardier has a worldwide fleet of approximately 5,000 aircraft in service with a wide variety of multinational corporations, charter and fractional ownership providers, governments, and private individuals. Bombardier’s Challenger and Global aircraft families are renowned for their cutting-edge innovation, cabin design, performance, and reliability. By their nature, forward-looking statements require us to make assumptions and are subject to important known and unknown risks and uncertainties, which may cause our actual results in future periods to differ materially from those set forth in the forward-looking statements.īombardier (BBD-B.TO) is a global leader in aviation, focused on designing, manufacturing, and servicing the world's most exceptional business jets. dollars, unless otherwise indicated.Ĭertain statements in this announcement are forward-looking statements based on current expectations. “We have built Bombardier to perform well with a solid company structure, and we continue to show great progress toward our raised 2025 objectives.”Īll amounts in this press release are in U.S. ![]() ![]() “Allow me to reiterate that I am very pleased with how we have started 2023,” added Demosky. Also, during the first quarter, Moody’s Investors Service upgraded Bombardier’s corporate family and Senior unsecured notes rating to B2. During the first three months of 2023, Bombardier also continued its strong progress on debt reduction with a repayment of approximately $400 million from cash on balance sheet and ended the first three months of 2023 with a stable, diversified $14.8 billion dollar backlog. “We remain focused on delivering a robust and predictable financial performance, all while providing an incredible experience to our valued customers.”Īs part of its recently published quarterly results for Q1 2023, Bombardier reported positive net income as well as higher year-over-year revenues and profit margins. This enhanced rating is a testament to Bombardier’s solid plan and financial discipline, as well as to the commitment of its talented teams,” said Bart Demosky, Executive Vice President and Chief Financial Officer. “This upgrade comes on the heels of a solid first quarter and reflects the company’s positive trajectory toward its objectives. S&P Global Ratings’ outlook for Bombardier remains stable. MONTREAL, (GLOBE NEWSWIRE) - Bombardier is pleased to share that S&P Global Ratings has upgraded the company’s credit rating from B- to B, citing solid execution, successful deleveraging efforts, backlog stability and effective management of supply chain risks as contributing factors as part of a release issued on May 1, 2023. All throughout the End Of The Road Tour, the band has stated that “any member is welcome to join us onstage.” The Kiss Army, myself included, hope original members Frehley and Criss rejoin Kiss with full face paint. To see the band walk away is a tough pill to swallow. For years I have grown up listening to Kiss, going to its shows and I have been a member of The Kiss Army. I for one do not want to see the band retire. Even Ozzy Osbourne recently decided to step away from the stage. If you look at the rock scene, The Who, Alice Cooper and The Rolling Stones are all up there in terms of age and are close to calling it a career. ![]() ![]() Who knows who will pick up the torch but someone has to do it, right? On one hand, the next 10 months are a celebration of all things Kiss but on the other hand, it’s the “changing of the guard” between rock bands. It’s not too often that you see three different artists be inspired by one single band.įor the music world, it’s bittersweet. One classic rock band, a pop star and a heavy metal band have all cited Kiss in one way or another. Kiss has inspired many artists and bands that have come after it across all generations and musical styles.īon Jovi, Lady Gaga and Pantera have recognized Kiss as an inspiration. So yes, while Styles and Beyoncé are cool, every trick they pull is a clone of a Kiss show. In the mid-1970s, Kiss wanted to put on a concert that its members would have wanted to see when they were young so they came up with shooting off fireworks, making the drum kit levitate as well as having guitars shoot off rockets and have smoke come from the inside. Now you might be saying to yourself, “I’ve seen Beyoncé or Harry Styles do this at their concert before.” Who do you think started all this? Bassist Gene Simmons spits out blood and flies on stage, guitarist Tommy Thayer shoots rockets out of his guitar and lead singer Paul Stanley flies on a zip line to a stage in the middle of the crowd. The hottest band in the world, Kiss!” and then it comes down to the stage from the roof on mini platforms.ĭuring the band’s shows, fireworks and pyrotechnics go off. That leaves us where we are right now, staring down the next 10 months before Kiss rocks Madison Square Garden for the final time.īefore every Kiss show, the band comes out to a recording that says, “You wanted the best, well you got the best. Nothing lasts forever – Frehley and Criss were replaced by current guitarist Tommy Thayer and the return of drummer Eric Singer. ![]() ![]() Ten years later, Bruce Kulick and Eric Singer were in the band only to be replaced by the original members again. By 1982 original guitarist Ace Frehley and original drummer Peter Criss left the band and were replaced by Vinnie Vincent and Eric Carr. According to the Recording Industry Association of America, the band’s next nine records, from 1976 to 1979, were certified platinum. Kiss’ music was built on classic 1970s rock and roll and the band wanted to be an artist it had never witnessed on stage, so its members put on face paint and created their own characters.Īfter the breakthrough of the band’s fourth overall record and first live record, “Alive!” Kiss-mania took the world by storm. When the legendary band Kiss appeared on “The Howard Stern Show” on March 1, it announced the final 50 shows of the bands’ career.įrom its self-titled debut record in 1974 to its last studio record in 2012, Kiss has outlasted most rock bands, reinvented the rock and roll wheel and inspired countless artists across every genre of music. ![]() The “X30 World” concept is based on the engine X30 125cc and it can be summarized in few words as “real Karting at hand”. These karts are fixed setup, which means they will be great to race online. ![]() There are two karts within the KartSim package, the Iame Senior X30 UK, and a Rental Kart, the karts have been meticulously designed working with partners on physics and drivers for performance and accuracy. Recently in 2011, an extension was added on to the track including a bridge, making it one of a kind. The circuit was built by Paul Fletcher, who still owns it today. British, European and World Championships are held at PFI, as well as a club race held once a month by Trent Valley Kart Club who are based at the track. PFI is the UK’s largest outdoor karting circuit based in Grantham, Lincolnshire and caters for various corporate events and race meetings throughout Lincolnshire, Newark, Nottingham and the UK. The track has various good overtaking opportunities, guaranteeing exciting races! It is no wonder all the young Racing Professionals start their career at GYG Karting.Ī lap around the track takes you through corners as a carousel, compression corner, the druid’s complex and the devil’s elbow and contains a straight named after the Snowdon Mountain. With fast, sweeping uphill and downhill sections combine to make this an extremely fun yet technical challenge. Situated on the A5 between Corwen and Betws-Y-Coed, is one of the UK premier karting venues that started life comparatively late to other S1 race venues. With a length of 1.6 km, this karting circuit is one of the largest in the UK. Situated in a woodland between the two motorways, its proximity to London makes it Britain’s busiest circuit.īuckmore Park is a circuit where many current and past Formula One drivers learned their trade, including Johnny Herbert and F1 champions Jenson Button and Lewis Hamilton, who was originally discovered by Ron Dennis in the 1996 Champions of the Future event held at Buckmore Park. Originally owned by John Surtees, who notably won world Grand Prix championships in both Formula One car racing and Grand Prix motorcycle racing. Included Tracks Buckmore Park International Circuitīuckmore Park Kart Circuit is an MSA approved outdoor kart racing circuit located just off the M2 in Chatham, Kent, England. The first KartSim pack for rFactor 2 is now available via Steam for 19,98€. In the near future, the KartSim team also plans to expand the portfolio of tracks and karts for KartSim with new and exciting content. ![]() You can race the X30 UK Senior Kart and Rental Kart on the laser-scanned Paul Fletcher International, Buckmore Park, and Glan Y Gors karting circuits. The first in a series of Kart packs features three tracks and two different types of karts. STUDIO 397 and third-party partner Tony Irfan are proud to announce that the KartSim DLC is now available for rFactor 2. ![]() ![]() It claims it has 190+ countries available.HideMyAss is rightfully considered one of the fastest VPNs.However, it does require a bank card to activate it. It runs on widespread VPN protocols OpenVPN and IKEv2.įirst, it’s the fact that it has a 7-day free trial. HideMyAss (HMA VPN, HMA!) is a popular paid Virtual Private Network service for all the major platforms. Low energy consumption, including on Android.Server lists for streaming and torrenting.If you are looking for a reliable VPN provider, HMA could be your choice. Its server locations cover more countries/locations than many VPN providers we have tested. HideMyAss VPN Review Conclusion:Īs one of the most popular VPN providers, Hide My Ass! (HMA!) Pro VPN provides stable VPN connections, fast VPN speed, a large number of worldwide server locations and easy to use software. We were able to get our questions answered using live chat. We tried using this method to get support and we were able to connect to a support representative immediately. On HMA’s website, there’s a live chat window where you can connect directly to its customer support team. Ping: 60 ms, Download: 21.31 Mb/s, Upload: 7.32Mb/s.Ĭonnected to HMA’s London server in the UK: Ping: 92 ms, Download: 28.49 Mb/s, Upload: 11.01 Mb/s.Ĭonnected to HMA’s Dallas, TX server in the United States:: Ping: 16 ms, Download: 49.68 Mb/s, Upload: 8.53 Mb/s.Ĭonnected to HMA!’s Los Angeles server in the United States:: Ping: 13 ms, Download: 69.04 Mb/s, Upload: 11.80 Mb/s.Ĭonnected to HMA!’s New York City server in the United States:: Below is the details of our VPN speed test results for HMA!: We used to measure the speed for ping, download and upload. We did our VPN speed tests for Hide My Ass! Pro VPN using a computer located in New York, NY, USA. Get HideMyAss VPN > HideMyAss VPN Speed Test: With HMA’s client software, users can connect/disconnect VPN, as well as to choose server locations and switch between different VPN protocols. The installation process is straight forward and the software interface looks clean: In addition, its VPN can be set up manually on the these operating systems and devices.įor our testing, we downloaded HMA’s client software for Windows. HMA provides free VPN software for Windows, MacOS, Linux, iOS, Android, TV and supported routers. Get HideMyAss VPN > VPN Software & Supported Operating Systems: HideMyAss Pro VPN offers a 30 day money-back guarantee for users to test out their VPN service. If you go with month-to-month, the price is $11.52 per month. If you pay every half year, the price is equivalent to $8.33 per month. HMA! Pro VPN’s price starts from $6.56/mo if you pay manually. If you use our VPN service for such activity, you will probably cause us to receive DMCA notices from the copyright holders, who monitor Torrent trackers.” Plans & Pricing: However, we do not support the use of Torrent to share copyrighted material illegally. If you want to connect more than 2 devices, you can either create a new account, or purchase a bulk account package.”įor P2P/Torrent traffic, here’s what HMA told us: “HMA! Pro VPN does support Torrent as this is a legitimate technology for sharing data over the internet. You can use a combination of any 2 devices, be it 2 computers, or one computer and one mobile phone, etc. Here’s what HMA’s customer support told us: “Our service can be set up on any number of devices, but you can only connect 2 at the same time. Get Hide My Ass ! Pro VPN > Feature Restrictions:įor simultaneous connections, HMA! Pro VPN allows two devices to be connected at the same time. If privacy is your top concern or you’re looking for a no-log VPN provider, HMA! might not be your best choice. These data is stored for between 2 to 3 months. It should be pointed out that HMA does keep some logs (including time stamp, amount of data transmitted, user’s real IP address and the IP address of the VPN server etc.). HideMyAss supports the following VPN protocols: OpenVPN (TCP, UDP), L2TP/IPsec and PPTP. There’re more than 120,000 IP addresses available for their HMA! Pro VPN users. HMA! has nearly 900 VPN severs in 300+ locations and 200+ countries. Number of Simultaneous Connections Allowed: 2 devices.Free Trail: 30 day money-back guarantee.Large number of world-wide servers to choose from. This is known as a comprehensive media player and music management software that is compatible with both Android and Windows operating systems. Released in 2001, MediaMonkey is a media player application that allows you to manage your digital video and music collection. Price of the ad-free version: One-time purchase for $29.00 5. Hardware compatibility, allows you to customize the video output according to your hardware specifications.Offer highly customizable features, for instance, adjusting the skins of the app, changing to font, size and color of subtitles adjust the brightness of the videos.Support playlist creation as well as create and manage files.Support a variety of audio options codecs, e.g.Support excellent subtitle system, for instance, SRT, SUB, and ASS.Support high-resolution videos without lag.Offer a variety of playback options, for instance, adjusting the playback speed.Compatible with various file formats, e.g.It is known for its versatility and features. This media player is able to play various types of media files like video, music, and DVDs. Similar to VLC and KMPlayer, BSPlayer was also launched in early 2000 and has been widely used by people across the world. Price of the ad-free version: One-time purchase for $0.99/month or $9.99/year 3. Kids lock, which restricts access to certain features. ![]()
![]() Great for extreme vibration applications as well. This International Protection rating means that your KeyLine isolator is safe for use even for your off-road needs in dusty, wet and unexpected extreme weather environments. RUGGED DURABILITY: Unlike other isolators on the market, the KeyLine Automatic 140 Amp Dual Battery Isolator is IP65 Certified.It’s like having two separate power sources for each battery while only having one alternator! Voltage Sensitive Relay (VSR) cuts in at 13.3 volts and cuts out at 12.8 volts to ensure your primary battery is always charged and ready to start your vehicle. VOLTAGE SENSITIVE RELAY: The KeyLine Automatic 140 Amp Dual Battery Isolator is all you need to charge Two Battery Systems.This compact battery isolator was built ultra-small (2.6″ x 2.6″ x 2″) to fit almost anywhere! A perfect fit under the hood to get close to your dual batteries. ZERO VOLTAGE DROP: Forget the traditional diode relays and so-called “solid state” devices that can rob you of almost 2 amps of output power! The KeyLine Dual Battery Isolator is the only unit designed with cutting edge programming to deliver optimum performance – with ZERO sacrifice. ![]() 100% SATISFACTION: no reason for return or change. Easy to use: this VSR comes with mounting plate and 4 bolts for install.Compatible: used for DC 12 V two battery systems isolate and charge, universal used for car, vehicle, RV, ATV, UTV and boat, also two battery electrical equipment. ![]()
(B) An example of RNA footprints from FLAG-CASC3:EIF4A3 containing complexes following 5′-end-labeling with ATP and resolution on a 26% Urea-PAGE gel. As seen in the figure, different complexes have different composition, as reflected by different levels of UPF2 protein in the three complexes. Cell lines expressing the endogenously tagged protein used in RIPiT are indicated above each lane. Western blots showing levels of the proteins (on the right) in various fractions labeled on the top (EL, elution FT, flowthrough). (A) An example of RIPiT validation via western blots. Visualization of proteins and RNAs enriched via RIPiT. With a 20–30% insertion efficiency and relatively small amplicon, there should be a clear shift of amplicon containing inserted tag (two replicates shown in lanes 2 and 3, labeled tagged locus) as compared to wild-type endogenous locus (single band in lane 1). (B) A bulk-level (i.e., in a pool of cells) analysis of CRISPR-mediated insertion efficiency by amplifying the insertion site with PCR 48–72h after guide RNA-Cas9 RNP complex electroporation. Primers (labeled Fwd and Rev) flanking the insertion site are used in the PCR reaction with genomic DNA as a template to identify the insertion event. Single-stranded oligo donor (ssODN) for homology-directed repair is on the top where FLAG tag sequence and a flexible linker (amino acid sequence GGGS) is flanked by 35–50nt DNA sequence with perfect homology with the DNA sequence surrounding the cut site (triangle) induced by guide RNA-Cas9 RNP complex. ![]() (A) Scheme of CRISPR-Cas9-mediated insertion of affinity tag (FLAG) into endogenous locus of a gene. All rights reserved.ĬRISPR-Cas9-mediated insertion of affinity tag and bulk assessment of tag insertion. ![]() High-throughput sequencing RIPiT RNA footprint RNA-binding protein Ribonucleoprotein.Ĭopyright © 2021 Elsevier Inc. This updated custom library preparation protocol is compatible with commercial PCR multiplexing systems for Illumina sequencing platform for simultaneous and cost-effective analysis of large number of samples. We present a modified protocol for library preparation for high-throughput sequencing so that it exclusively uses equipment and reagents available in a standard molecular biology lab. In this protocol, we have used CRISPR-Cas9 to introduce affinity tag to endogenous protein of interest to capture a more representative state of an RNP complex. Here, we provide an updated and improved protocol for RIPiT-seq. To fill this gap, we have previously developed RNA Immunoprecipitation in Tandem followed by high-throughput sequencing (RIPiT-seq) to characterize RNA targets of compositionally distinct RNP complexes by sequentially immunoprecipitating two proteins from the same RNP and sequencing the co-purifying RNA footprints. While powerful techniques are available to identify binding sites of individual RBPs at high resolution, it remains challenging to unravel binding sites of multicomponent ribonucleoproteins (RNPs) where multiple RBPs or proteins function cooperatively to bind to target RNAs. The ability to identify RNA targets bound by RBPs is critical for understanding RBP function. Construction is underway at some of the parks but has been delayed because of the pandemic, but estimates still put that opening some time in 2023.RNA-binding proteins (RBPs) regulate all aspects of RNA metabolism. In this immersive land, guests will be able to participate in a real-life video game, doing things that Mario does, like hitting bricks (in real life) to collect coins collected virtually on a wristband. The announcement comes after Universal announced a Super Nintendo World at its parks in Florida, California, China and Japan. The Jurassic World VelociCoaster is scheduled to open in summer 2021. ![]() An amphibian Mososaurus tries to break through its tank, and there are encounters with raptors, T-Rex and the massively frightful Indominus Rex. The two parks share a flume ride: what is Jurassic Park River Adventure in Florida was updated to a much more technologically advanced Jurassic World: The Ride in California in 2019. There are also Jurassic Park-themed Kids Suites at Loews Royal Pacific Hotel at Universal Orlando. The Jurassic Park land in Orlando is significantly more extensive than in Hollywood-you can take photos with real jeeps from the movies (which are only visible on the Studio Tour in the other park), and there are a Pteranodon Flyers kids ride and a Jurassic Park Discovery Center that lets you explore the dinosaurs. ![]() This is the first Jurassic Park roller coaster for any Universal park, and is in the dinosaur area that’s also home to rides, restaurants and character experiences. A rendering of the new VelociCoaster at Universal's Islands of Adventure Universal Orlando ![]() ![]() One of the biggest rumors about a potential second season is the inclusion of the Kang Variant Rama-Tut. Release Option 2: Moon Knight Returns In Time For Avengers 5 Marvel So, once again, even if a Moon Knight follow-up could get itself off the ground imminently, there simply isn't room to fit it into the roster until at least 2025. On top of the already announced 2024 slate, Marvel Studios also has Wonder Man on the way to Disney+, and that appears to be far closer to release than Moon Knight Season 2 given it has already begun production. However, that would require production to begin imminently and there is currently no evidence pointing toward that. The earliest logistically possible release date for Moon Knight Season 2 would likely be the later portion of 2024. Release Option 1: Moon Knight Rounds Out 2024 Marvel That’s not even including Echo, which might also be included if the project doesn’t make it out of the gates by the end of 2023 - although the latest update offers positive signs on that front. Ironheart, Agatha: Coven of Chaos, and the 18-episode Daredevil: Born Again are all expected to release in that window, meaning more than half the year is already occupied for weekly releases. Not to mention, next year’s MCU Disney+ release slate is already filled to the brim. Secondly, filming doesn't appear anywhere close to starting up yet, and it would need to be just around the corner if it hopes to make it onto Disney+ in early 2024. Even if production somehow began right now, it would still be near-impossible for Marvel Studios to pull off and fit into the slate.įor one, a second season has still not been confirmed by Marvel Studios. Could Moon Knight Return Next Year? MarvelĪ release anytime in 2024 is by far the least likely scenario for Moon Knight Season 2. However, looking at the MCU's plans for the coming years combined with rumors and reports, a release window can be narrowed down. ![]() With Moon Knight Season 2 still yet to be announced, Marvel Studios has yet to confirm a release date. There have been plenty of rumors regarding a second season, but the star himself admitted that “ don’t know” if there will be another batch of episodes. However, there are no indications of when fans will be seeing Isaac’s hero again. Its first season even ended with a big cliffhanger-one that begs further exploration. The Disney+ series is one of the best-received streaming series from Marvel Studios. When might a hypothetical second season of Oscar Isaac’s Moon Knight fit into the Marvel Cinematic Universe tapestry? Our representatives can help you to find a special alcoholism treatment that will land within your budget. 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